addGCBintoMethylome

This function is used to add GC bin to the methylation sites and calculate the average methylation for each bin.

Usage

addGCBintoMethylome(msites, gcdist, ignoreStrand = TRUE)

Arguments

msites

Imported methylation sites using read_methylome function

gcdist

a GRanges object contains Genome wide GC distribution

ignoreStrand

• if TRUE, it ignores strand info from annotation

Value

a matrix object with GC bin with corresponding avg methylation

Author

Irem Gunduz

Examples

library(methylTFR)

# Load the data
load(system.file("extdata",
    "gcdist_subset.rda",
    package = "methylTFR"
))
load(system.file("extdata",
    "example_data.rda",
    package = "methylTFR"
))

# Add GC bin
bin_meth <- addGCBintoMethylome(msites, gcdist)