Resting-vs-stimulated allele-specific TF activity scatter

Each point is a TF: x = activity in resting, y = activity in stimulated. Points are coloured by TF family (ascTFFamily) and faded when not significant in either context. Points above the diagonal gain allele-specific activity on stimulation (amplification); the two families typically separate into opposite quadrants. (This replaces the earlier "handoff/flip" framing, which the data did not support.)

plotASCTFActivityScatter(switchDt, topN = 18L, sigCut = 0.1)

Arguments

switchDt

output of ascTFActivitySwitch.

topN

number of TFs (by |deltaObs|) to label (default 18).

sigCut

FDR threshold for the significance fade (default 0.1).

Value

a ggplot.

Author

Irem B. GUNDUZ